(Portland, OR) -- Portland remains one of the nation's biggest hotspots for rats and mice. That's according to a new report from pest control Terminix, which ranks Portland 33rd on its list of the top 50 cities with the most rodent problems. Terminix says large populations, food waste and plenty of places for rodents to hide all contribute to the problem. The ranking is based on where the company received the most rodent-control service calls in 2025. Health officials warn rats and mice can spread disease and encourage residents to keep food sealed, secure trash containers and close off entry points to their homes.